GrotonFull TimeEngineering
Remotely
thermal analysisramandissolutionhot melt extrusiondrug formulationamorphous solid dispersionsspray dried dispersionstablet design
Job Description
📋 Description
- Prepare prototype formulations for exploratory studies in in-vitro and in-vivo models
- Develop oral, topical and sterile dosage forms for feasibility studies and small-scale manufacturing
- Measure key formulation properties (solubility, tablet hardness, disintegration, pH, isotonicity
- Assess chemical/physical stability and performance of prototypes using in-vitro tests
- Identify stability and performance issues with prototype formulations
- Develop protocols for formulation preparation at preclinical/clinical study sites
🎯 Requirements
- Experience with drug formulation and pre-formulation techniques
- Experience with amorphous solid dispersions (spray dried dispersions or hot melt extrusion) and
- Basic chemistry laboratory experience (wet or solid state)
- Experience with lab equipment and mechanical aptitude
- Experience with advanced characterization techniques such as Raman, thermal analysis and dissolution
- Ability to follow procedures reliably and maintain accurate records
🎁 Benefits
- Full-time schedule, Monday to Friday, with potential weekend/overtime as needed
- Comprehensive medical, dental and vision coverage
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
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