Associate Scientist II, in vitro Preclinical Development

📋 Description

• Develop and perform cell-based assays for mRNA-tLNP programs from discovery to IND-enabling studies.
• Execute in vitro assays to assess T-cell reprogramming, cytotoxicity, function, and immune
• Isolate PBMCs and T cells from leukopaks.
• Culture mammalian cells using aseptic techniques; work with tumor lines, T cells, and PBMCs.
• Create stable tumor cell lines via electroporation, viral delivery, and nanoparticle transfections.
• Maintain good laboratory practices and accurate online lab notebooks; validate instruments/reagents