Job Description
📋 Description Lead ADME/PK strategies for pre-targeted therapeutics (biologics & small molecules). Define PK/PD and biodistribution strategy to support validation and programs. Partner cross-functionally with chemistry, protein engineering, bioanalytical, and tox teams. Serve as the PK subject matter expert for pre-targeting systems and click therapeutics. Design, analyze, and interpret PK, biodistribution, and mass balance studies. Build PK/PD and mechanistic models to predict human dosing. 🎯 Requirements PhD in Pharmacokinetics, Pharmaceutical Sciences, Bioengineering, or related field. 4+ years of industry ADME/PK leadership on therapeutic programs. Deep expertise in PK of biologics and targeted delivery systems. Strong experience designing and interpreting in vivo PK and biodistribution studies. Demonstrated experience with QSP and PK/PD modeling. Experience with modeling tools (Phoenix WinNonlin, NONMEM, Monolix, MATLAB). 🎁 Benefits Equity included as part of total compensation. Comprehensive benefits: medical, dental, vision, 401(k) match, disability. Flexible PTO and a WFH stipend to support remote work. Remote-first company with occasional travel for in-person meetings. Core collaboration window: 9:00am–3:00pm Pacific Time. Growth opportunities, professional development, and mentorship.
